UNUSUAL NEUROLOGICAL MANIFESTATIONS OF PRIMARY HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

The nervous system may be involved during primary human immunodeficien cy virus (HIV) infection. Recognized clinical syndromes include mening itis, meningo-encephalitis, myelopathy, polyneuropathy and rhabdomyoly sis. We report three patients with unusual neurological presentations of primary HIV infection: intracranial hypertension, severe encephalop athy characterized by personality changes and regressive behavior, and iumbosacral radiculoneuropathy. In all, the neurological disorder had a benign course and resolved within a few months. Awareness of the la rge spectrum of neurological manifestations of primary HIV infection c an enable early diagnosis and treatment. Eur J Neurol 5:369-373 (C) 19 98 Lippincott-Raven Publishers.