A 67-year-old woman who developed acute secondary mania immediately af
ter a mixed (perforating and cortical) embolic brain infarction in the
territory of the right middle cerebral artery is described. According
to neuroradiological findings ischemic lesions involving the basal an
d medial areas of the temporal lobe and the head of the caudate as wel
l as the putamen were evident. In the pathogenesis of secondary mania
due to cerebrovascular disease, the pattern of involved structures is
unique and underlines the significance of lesion location after damage
of the minor hemisphere. Eur J Neurol 5:407-409 (C) 1998 Lippincott-R
aven Publishers.