Disordered motility of the gastrointestinal tract in children is usual
ly manifest as gastro-oesophageal reflux disease. Reflux is common in
infants but usually resolves spontaneously with time. If severe enough
to merit investigation, 24-hour ambulant oesophageal pH monitoring is
the most widely used investigation, though lit does have disadvantage
s. Upper gastrointestinal endoscopy and biopsy may be required to diag
nose oesophagitis, Treatment follows a step-wise approach, progressing
from positioning and feed-thickening in infants, through to pharmacol
ogical management with prokinetic agents and/or acid-suppression, and
surgery for a very small proportion of children whose symptoms do not
respond to optimal medical therapy. (C) 1998 Lippincott-Raven Publishe
rs.