GENE-THERAPY FOR BREAST-CANCER

Citation
Hke. Boxhorn et Sl. Eck, GENE-THERAPY FOR BREAST-CANCER, Hematology/oncology clinics of North America, 12(3), 1998, pp. 665
Citations number
63
Categorie Soggetti
Oncology,Hematology
ISSN journal
08898588
Volume
12
Issue
3
Year of publication
1998
Database
ISI
SICI code
0889-8588(1998)12:3<665:GFB>2.0.ZU;2-Q
Abstract
Gene therapy for breast cancer is still in the very early stages of de velopment. Many of the molecular strategics that have been proposed ar e also being developed for other cancers. Their application to breast cancer, however, needs to address several issues specific to this dise ase such as the widespread nature of metastases the indolent growth of the tumor cells, and the production by the tumor of immunosuppressive agents. Nonetheless, these approaches appear promising, particularly those that employ a combination of strategies. Gene therapies that aff ect the biology of breast cancer cells or regulate host immun mechanis ms have bren most successful and may be paired with existing therapies for breast cancer.