J. Erhard et al., AUXILIARY LIVER-TRANSPLANTATION WITH ARTERIALIZATION OF THE PORTAL-VEIN FOR ACUTE HEPATIC-FAILURE, Transplant international, 11(4), 1998, pp. 266-271
Six adult patients suffering from acute hepatic failure and with a hig
h urgent status underwent heterotopic auxiliary liver transplantation.
In four of these patients, the portal vein of the liver graft was art
erialized in order to leave the native liver and the liver hilum untou
ched and to be able to place the liver graft wherever space was availa
ble in the abdomen. The arterial blood flow via the portal vein was ta
pered by the width of the anastomosis. Two patients died! one of sepsi
s on postoperative day 17 (POD), the other after 3 months due to a sev
ere CMV pneumonia. There were no technically related deaths. The nativ
e liver showed early regeneration in all cases. In one patient, the au
xiliary graft was removed 6 weeks after transplantation. Four weeks la
ter, he had to undergo orthotopic retransplantation due to a recurrent
fulminant failure of the recovered native liver. This patient is aliv
e more than 1 year after the operation. We conclude that heterotopic a
uxiliary liver transplantation with portal vein arterialization is a s
uitable approach to bridging the recovery of the acute failing native
liver.