PRENATAL-DIAGNOSIS OF A DER(X)T(X-15)(P22.2-Q11.2) INHERITED FROM A MATERNAL TRANSLOCATION X-15

Authors
GARCIAHERAS J ULM JE SHAVER DE HALL E SAIKEVYCH IA
Citation
J. Garciaheras et al., PRENATAL-DIAGNOSIS OF A DER(X)T(X-15)(P22.2-Q11.2) INHERITED FROM A MATERNAL TRANSLOCATION X-15, Prenatal diagnosis, 18(7), 1998, pp. 747-750
Citations number
18
Categorie Soggetti
Genetics & Heredity","Obsetric & Gynecology
Journal title
Prenatal diagnosis → ACNP
ISSN journal
01973851
Volume
18
Issue
7
Year of publication
1998
Pages
747 - 750
Database
ISI
SICI code
0197-3851(1998)18:7<747:POADIF>2.0.ZU;2-I
Abstract
A karyotype 46,X,der(X)t(X;15)(p22.2;q11.2) derived from a maternal tr anslocation X;15 was ascertained in a female fetus through an abnormal triple screen test at 16 weeks that gave a 1/56 risk for Down syndrom e. The pregnancy was terminated at 19.5 weeks and anatomopathologic st udies showed fewer malformations than other fetal trisomies 15. This i s the first prenatal identification of an unbalanced t(X;15). (C) 1998 John Wiley & Sons, Ltd.