ACYLATION OF GUANYLHYDRAZONES DERIVED FROM CYCLIC-KETONES - SYNTHESISOF YLAMINO-1-CYCLOALKENYL-5-METHYL-1H-1,2,4-TRIAZOLES

Reaction of guanylhydrazones derived from different cycloalkanones, 1- indanone and 4-chromanone, respectively, with excessive acetic anhydri de leads to the formation of lamino-1-cycloalkenyl-5-methyl-1H-1,2,4-t riazoles. However, with camphor guanylhydrazone only tine correspondin g N,N'-diacetyl-guanylhydrazone was obtained, whereas 2-adamantone gua nylhydrazone afforded etylamino-5-methyl-1,2,4-triazol-1-yl)-2-adamant yl acetate. Detailed NMR spectroscopic studies (H-1,C-13) With the tit le compounds and their guanylhydrazone precursors are presented.