Objectives: In North America and Europe, it is usually assumed that bi
ological changes associated with the end of menstruation and the onset
of specific diseases commonly associated with the postmenopausal cond
ition are universal. Using an anthropological approach in which menopa
use is understood as a concept that is historically and culturally pro
duced, an argument is made for additional systematic investigation of
what protects the majority of women from distress at menopause, and wh
at factors contribute to a healthy old age. Method: Survey research ba
sed on questionnaire responses, together with open-ended interviews an
d textual analyses, were used. Results: Differences are demonstrated i
n postmenopausal experiences and symptom reporting in Japan as compare
d with Canada and the United States. Reporting of hot flashes and nigh
ts sweats is significantly lower in Japan. These findings, together wi
th the well established figures about greater longevity and lower inci
dence of heart disease, breast cancer, and osteoporosis in Japan, comp
ared with North America, indicate that cultural and biological variabl
es act in concert to produce this variation. Theories about the evolut
ion of menopause and demographic data on aging are also discussed. Thi
s data challenges the widely held assumption that populations of postm
enopausal women only recently have come into existence because of cult
ural and technological interventions. Conclusions: Postmenopausal wome
n have been present in human populations since homo sapiens first evol
ved. Culturally mediated life styles affect both the menopausal experi
ence and the health of women as they age. Additional investigations ar
e needed.