CHEMOATTRACTANT FACTORS AND THE CONTROL OF HUMAN-IMMUNODEFICIENCY-VIRUS REPLICATION

Authors
BAIER M BANNERT N WERNER A ADLER HS OTTEKEN A BEER B NORLEY S KURTH R
Citation
M. Baier et al., CHEMOATTRACTANT FACTORS AND THE CONTROL OF HUMAN-IMMUNODEFICIENCY-VIRUS REPLICATION, Pathobiology, 66(3-4), 1998, pp. 128-130
Citations number
21
Categorie Soggetti
Cell Biology",Pathology
Journal title
Pathobiology → ACNP
ISSN journal
10152008
Volume
66
Issue
3-4
Year of publication
1998
Pages
128 - 130
Database
ISI
SICI code
1015-2008(1998)66:3-4<128:CFATCO>2.0.ZU;2-P
Abstract
Factors secreted by CD8(+) T cells have been described to suppress imm unodeficiency virus replication. The research efforts to identify thes e factors led to the proposal of some candidate proteins as being resp onsible for the antiviral effects. Chemokines and IL-16 are secreted b y CD8(+) T cells and inhibit HIV replication through different mechani sms. However, their antiviral properties cannot fully explain the inhi bitory activities found in cell culture supernatants from CD8(+) T cel ls.