DIPEROXOVANADATE PARTICIPATES IN PEROXIDATION REACTIONS OF H2O2 IN PRESENCE OF ABUNDANT CATALASE

Authors
RAO AVS RAVISHANKAR HN RAMASARMA T
Citation
Avs. Rao et al., DIPEROXOVANADATE PARTICIPATES IN PEROXIDATION REACTIONS OF H2O2 IN PRESENCE OF ABUNDANT CATALASE, Biochimica et biophysica acta (G). General subjects, 1381(2), 1998, pp. 249-255
Citations number
35
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta (G). General subjects → ACNP
ISSN journal
03044165
Volume
1381
Issue
2
Year of publication
1998
Pages
249 - 255
Database
ISI
SICI code
0304-4165(1998)1381:2<249:DPIPRO>2.0.ZU;2-I
Abstract
Vanadate forms a stable complex with H2O2 at pH 7.0 in competition wit h catalase and the product, diperoxovanadate, resists scavenger action of catalase. Diperoxovanadate can act as a substrate in a H2O2-user r eaction, horseradish peroxidase and can take the place of H2O2 far mor e effectively in oxidatively inactivating glyceraldehyde-3-phosphate d ehydrogenase. By forming peroxo-complexes vanadate can provide a way o f preserving cellular H2O2 in presence of abundant catalase and make i t available for its functions. (C) 1998 Elsevier Science B.V. All righ ts reserved.