Y. Hirai et al., NEW MONOTERPENTRIOLS FROM THE FRUITING BODY OF FLAMMULINA VELUTIPES, Bioscience, biotechnology, and biochemistry, 62(7), 1998, pp. 1364-1368
Two monoterpentriols were isolated from the stipe segment without eith
er the pileus or apical growth zone of the harvested fruiting body of
I;. velutipes. The structures of these monoterpentriols were elucidate
d as (1R, 2R, 4R, 8S)-(-)-p-menthane-2,8,9-triol (1) and its 8-epimer
(2) based on a spectroscopic analysis and stereoselective chemical tra
nsformation from an authentic monoterpene alcohol. These monoterpentri
ols showed growth-promoting activities on the excised stipe with the p
ileus segment, which had been excised from a fruiting body just under
the growth zone before the middle stage of the rapid growth period, at
concentrations below 10 ppm, while the growth of the segment was inhi
bited at concentrations of 100 ppm and above.