Purpose: To characterize a newly recognized maculopathy, benign foveal
depigmentation, Methods: Three patients with unusual foveal depigment
ation mere prospectively studied. Results: The patients were referred
with a diagnosis of Stargardt's macular dystrophy. Ophthalmic examinat
ion revealed discrete, bilateral, symmetric, oval foveal depigmentatio
n, This appeared to be at the level of the retinal pigment epithelium,
These patients were followed for up to ten years with stable vision a
nd Ilo change in lesion size. Conclusions: Benign foveal depigmentatio
n is a maculopathy which has discrete, bilateral, symmetric, horizonta
lly oval foreal depigmentation at the level of the retinal pigment epi
thelium, This appears to be visually benign.