SYNTHESIS OF 3-OCTYL-3-(PROP-2-YNYL)PYRROLIDINE-2,5-DIONE, LOHEXYLMETHYL-3-(PROP-2-YNYL)PYRROLIDINE-2,5-DIONE AND 3-CARBOXY-3-(PROP-2-YNYL)PYRROLIDINE-2,5-DIONES REQUIRED AS POTENTIAL AROMATASE INHIBITORS

Authors
WOO LWL SMITH HJ BARRELL KJ NICHOLLS PJ
Citation
Lwl. Woo et al., SYNTHESIS OF 3-OCTYL-3-(PROP-2-YNYL)PYRROLIDINE-2,5-DIONE, LOHEXYLMETHYL-3-(PROP-2-YNYL)PYRROLIDINE-2,5-DIONE AND 3-CARBOXY-3-(PROP-2-YNYL)PYRROLIDINE-2,5-DIONES REQUIRED AS POTENTIAL AROMATASE INHIBITORS, Journal of the Chemical Society. Perkin transactions. I, (21), 1993, pp. 2549-2553
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
21
Year of publication
1993
Pages
2549 - 2553
Database
ISI
SICI code
0300-922X(1993):21<2549:SO3L>2.0.ZU;2-X
Abstract
Routes are described for the synthesis of 3-alkyl-3-(prop-2-ynyl)pyrro lidine-2,5-diones 5 and 6, which are not available by the literature m ethod for the corresponding prop-2-enyl analogues, and 3-carboxy-3-(pr op-2-ynyl)pyrrolidine-2,5-dione 7.