INVESTIGATION ON SOME REACTIONS OF SACCHARINYL BENZOIC-ACID AZIDES

Authors
ARIEF MMH
Citation
Mmh. Arief, INVESTIGATION ON SOME REACTIONS OF SACCHARINYL BENZOIC-ACID AZIDES, Phosphorus, sulfur and silicon and the related elements, 127, 1997, pp. 159-165
Citations number
8
Journal title
Phosphorus, sulfur and silicon and the related elements → ACNP
ISSN journal
10426507
Volume
127
Year of publication
1997
Pages
159 - 165
Database
ISI
SICI code
1042-6507(1997)127:<159:IOSROS>2.0.ZU;2-Q
Abstract
Saccharinyl benzoic acid azides 2a-c were used to synthesize a number of noncondensed heterocyclic systems. Thus azides 2a or 2c reacted wit h glycine to give 1,3-oxazolin-5-one derivatives 3a and 3b. However az ide 2b reacted to give diaryl urea derivative which was easily cyclize d to give imidazol -2,5- dione (6). Also azides 2a-c reacted with glyc olic acid to give 1,3-oxazolin -2,5-dione derivatives (7a-c) and with aroyl hydrazines to give the corresponding hydrazides (8a-f) which wer e cyclized to 1,3,5-oxadiazole derivatives (9a-f).