Ng. Kundu et Sk. Dasgupta, SYNTHESIS OF 5-(ACYLETHYNYL)URACILS AND THEIR CORRESPONDING 2'-DEOXYRIBONUCLEOSIDES THROUGH PALLADIUM-CATALYZED REACTIONS, Journal of the Chemical Society. Perkin transactions. I, (21), 1993, pp. 2657-2663
Good yields of the title uracils were obtained by using the palladium-
catalysed reaction between 5-iodo-2,4-dimethoxypyrimidine and substitu
ted propargylic alcohols rather than the corresponding ketones. The sa
me strategy works for coupling with the 5-iodo-2'-deoxyuridines.