GLIOFIBROMA - MIXED GLIAL AND MESENCHYMAL TUMOR - REPORT OF 3 CASES

Gliofibromas are rarely encountered astrocytic tumours comprising of a strocytic and benign fibroblastic components. They commonly occur in f irst two decades of life. However, the exact behaviour is not fully kn own and their histogenesis is also still debatable. We report three ca ses of gliofibroma in which we studied proliferative markers (MIB-1) a nd p53 protein expression. In these tumours, occurrence in adult life is in contrast to that reported in the literature. Depending upon the morphology and proliferative Labelling Index we classified these tumou rs into low grade (benign) and high grade (malignant/anaplastic). (C) 1998 Elsevier Science B.V. All rights reserved.