The objective of the glossary is to provide in a single document a con
sistent terminology and concise definitions of terms covering the vari
ous aspects of medicinal chemistry. This was felt necessary with regar
d to the rapid changes occurring in medicinal chemistry and also by th
e need to establish international definition standards. Effectively th
e possibility exists that in different countries certain terms may not
have the same meaning, in such a case the creation of an internationa
lly accepted definition is particularly justified. A Working Party bel
onging to the IUPAC Section on Medicinal Chemistry has therefore been
assembled which prepared the present glossary. Concise but sufficientl
y explanatory definitions have been formulated for about one hundred c
ommonly employed terms which can be considered of particular interest
to the medicinal chemistry community. The glossary has been compiled i
n part from definitions proposed by the Working Party in part from ear
lier IUPAC glossaries and in part from well-accepted definitions taken
from the literature but which were sometimes published in journals or
books that may not be readily accessible.