DIABETIC NEUROPATHY

Better clinical characteristics and a standardized approach to the def inition of neuropathy has enabled us to define more precisely the natu ral history of diabetic neuropathy Detailed studies on the pathology a nd pathogenesis have allowed dissection of important pathogenetic path ways. Effective treatment is currently limited, although a number of n ew and potentially important therapeutic interventions, including modi fication of the vascular supply and antioxidant status and growth fact ors, may prove to be of benefit in preventing damage and also promotin g repair of peripheral nerves in human diabetic neuropathy.