Objective: To determine if the sex ratio of live births in the United
States has changed during the 27 years from 1969 through 1995. Design:
Regression analysis of secular trends in sex ratios. Setting: Populat
ion-based data. Patient(s): Liveborn infants in the United States 1969
-1995. Main Outcome Measure(s): Sex of liveborn infant. Result(s): The
sex ratio (number of male births divided by number of female births)
declined significantly among whites during the 27 years under study. A
mong black newborns, the sex ratio significantly increased during the
same time period. Conclusion(s): These secular trends could not be exp
lained by changing maternal or paternal age, or by changing proportion
s of specific birth orders. Possible explanations for the observed cha
nges in sex ratio include random fluctuations in sex ratio over time,
changes in demographic characteristics of the population (other than t
he characteristics controlled for in this analysis), and changes in fr
equency or timing of intercourse. Environmental exposures are unlikely
to account for the observed trends. (Fertil Steril(R) 1998;70:270-3.
(C)1998 by American Society for Reproductive Medicine.).