We investigate the Turaev-Viro invariant (partition function) for 3-ma
nifolds with a boundary. In the framework of a TQFT, the partition fun
ction Z(M; Sigma 1, Sigma 2) of such a manifold can be interpreted as
a transition amplitude for topology change Sigma(1) --> Sigma(2) in 3D
gravity. We show that for S-2 boundaries Z(M; S-2) factorizes into a
term which contains the boundary dependence and another which depends
only on the topology of the underlying manifold. For a general T-g bou
ndary this factorization holds only in a particular case. We construct
specific examples of partition functions for the 3-ball B-3, the cyli
nder S-2 x 1 and the genus-1 handlebody H-1.