S. Shiomi et al., A CASE OF CAP POLYPOSIS INVESTIGATED BY SCINTIGRAPHY WITH HUMAN SERUM-ALBUMIN LABELED WITH TC-99M DTPA, Clinical nuclear medicine, 23(8), 1998, pp. 521-523
Cap polyposis is a rare intestinal disease that can be difficult to di
fferentiate from inflammatory bowel disease, When cap polyposis is sus
pected, it is important to confirm protein loss. A 54-year-old woman w
ho had been treated for ulcerative colitis for 7 years had severe hypo
proteinemia, Scintigraphy with Tc-99m-labeled DTPA complexed with huma
n serum albumin showed protein loss from the descending colon. Left he
micolectomy and sigmoid colectomy were performed. Cap polyposis was di
agnosed on the basis of histologic findings from an operative specimen
. The patient's diarrhea resolved after surgery and her hypoproteinemi
a improved. Scintigraphy with this label gave information helpful in t
he diagnosis of cap polyposis.