SPLENIC PELIOSIS WITH SPONTANEOUS SPLENIC RUPTURE IN A PATIENT WITH IMMUNE THROMBOCYTOPENIA TREATED WITH DANAZOL

We present a 79-year-old man diagnosed with immune thrombocytopenia (I TP), treated with danazol, who died as a result of a spontaneously rup tured spleen. The histopathological diagnosis was splenic peliosis. Th is patient presents a chronological association between the treatment with danazol and the development of pellosis, which suggests a clear c ause-effect relationship. pacing an Individual patient with ITP, clini cians should weigh the potential benefits of danazol with the possible development of serious complications, such as hepatic failure or sple nic rupture due to peliosis.