Lhj. Eberhart et al., THERAPEUTIC SUGGESTIONS GIVEN DURING NEUROLEPT-ANESTHESIA DECREASE POSTOPERATIVE NAUSEA AND VOMITING, European journal of anaesthesiology, 15(4), 1998, pp. 446-452
A double-blind randomized study was performed in 100 patients undergoi
ng thyroidectomy to evaluate the effect of positive therapeutic sugges
tions made during neurolept-anaesthesia. The classic droperidol-fentan
yl-N2O technique was used as these drugs preserve the neurophysiologic
al functions required to process the information in the therapeutic su
ggestions given during general anaesthesia. Patients in the suggestion
group heard positive non-affirmative suggestions during the whole ope
ration. An autoreverse tape player was used. The control group listene
d to an empty tape. Both groups were comparable with respect to demogr
aphic variables, anaesthetic technique, drug dosage, duration of anaes
thesia and surgery. Patients in the suggestion group suffered signific
antly less from post-operative nausea or vomiting (suggestion: 47.2% v
s, control: 85.7%) and required less anti-emetic treatment (suggestion
: 30.6% vs, control: 68.6%). We conclude that therapeutic suggestions
heard during neurolept-anaesthesia are processed and decrease post-ope
rative nausea and vomiting in patients after thyroidectomy.