According to WHO estimations, about 3% of the world population may be
infected with the hepatitis C virus. The relative prevalences of subty
pes of this virus vary in different geographic areas. The main known r
outes of transmission are parenteral; intravenous drug abuse, contamin
ated injection devices and receipt of unscreened blood. Sexual, vertic
al, household and nosocomial transmissions may occur, but seem to be r
are. The risk of screened blood or blood products is now almost elimin
ated, but unscreened blood is a considerable risk in areas where scree
ning is economically not possible. The future impact of this virus is
greatly dependent on the trends in intravenous drug use as well as the
possible emergence of increased late morbidity among present asymptom
atic carriers during the next decades.