ANALYSIS OF CD34-EXPRESSING CELLS IN CLINICAL-PRACTICE

The flow cytometric determination of haemopoietic cells defined as CD3 4-expressing cells has greatly added to the improvement of the managem ent of harvesting circulating haemopoietic cells for subsequent autolo gous reinfusion in the setting of high-dose chemo/(radio)-therapy. Add itionally, this flow cytometric determination has replaced, in some in stitutions, the in-vitro culture test for CFU-GM as the measure to est imate the haemopoietic potential of the cells to be reinfused/transpla nted.