Does regional economic integration affect the location of economic act
ivity inside countries? Discussed in this paper is recent academic lit
erature on whether the movement towards free trade in North America ha
s influenced the spatial organization of production ill Canada, Mexico
, or the United States. In Mexico, closer economic ties with the Unite
d States appear to have contributed to a contraction of employment in
the Mexico City manufacturing belt, a rapid expansion of manufacturing
employment in northern Mexico, and an increase in the wage premiums p
aid to skilled workers. The effects of economic integration on industr
y location in Canada and the United States seem to have been much weak
er. One exception to this finding is US cities on the Mexican border,
whose employment growth is strongly positively correlated with export
production in neighbouring Mexican regions. The implication of a possi
ble hemispheric free-trade agreement are also discussed.