NUCLEAR MATRIX OF HUMAN OVARIAN-CANCER CELLS IN-VITRO

The epithelial neoplasia constitute 60% of all primary tumors of the o vary and 90% of these are malignant. Nuclear matrix has been found to be involved in normal and abnormal nuclear activities. Previously, we have identified tumor-associated nuclear matrix: proteins in cancers o f human liver, nasopharynx and cervix. In this study, we compared nucl ear matrices of immortalized ovarian and cancer cell lines by morphome tric and 2-D gel electrophoresis analysis.