SERUM LEPTIN, FOOD-INTAKE AND PREFERENCES FOR SUGAR AND FAT IN OBESE WOMEN

OBJECTIVE: To examine the association of leptin with food intake and p references for sugar and fat in obese humans. METHOD: Food intake and preferences for sugar and fat were measured in 35 obese women by a fou r-day food record and three hedonic tests, respectively. RESULTS: High fasting serum leptin concentration adjusted for body fat mass and die tary underreporting was associated with low dietary energy and fat int akes. In addition, trends towards lower preference for chocolate as we ll as for the taste of high-fat, low-sugar mixture were observed in th ose with higher leptin concentration. CONCLUSION: High serum leptin co ncentration could be associated in obese women with lower dietary ener gy and fat intakes, and possibly with the lower preference for fat. Th ese findings need to be verified in further human studies.