Dr. Radford et al., ADHERENCE OF CANDIDA-ALBICANS TO DENTURE-BASE MATERIALS WITH DIFFERENT SURFACE FINISHES, Journal of dentistry, 26(7), 1998, pp. 577-583
Objectives: To assess the in vitro adherence of Candida albicans to he
at-cured hard and soft denture-base materials with varying surface rou
ghness, and to observe the effect of a mixed salivary pellicle on cand
idal adhesion to these surfaces. Methods: In vitro adhesion assays on
heat-cured acrylic resin (Trevalon), Molloplast B and Novus using the
type strain of C, albicans (NCPF 3153A). Surfaces for the assays were
prepared using clinically appropriate rotary instruments. Unstimulated
, pooled and clarified whole saliva was used to assess its effect on a
dhesion. Results: Significantly greater adhesion of C. albicans to rou
gh rather than smooth surfaces was found (P < 0.001), as well as incre
ased adhesion to the machined soft lining materials compared with acry
lic. Pre-coating denture-base materials with saliva reduced candidal a
dhesion on all materials. Conclusions: Rough surfaces on denture-base
materials promote the adhesion of C. albicans in vitro. However, saliv
a reduces adhesion of C. albicans and thus diminishes the effect of su
rface roughness and free surface energy differences between materials.
(C) 1998 Elsevier Science Ltd. All rights reserved.