Gp. Tzagarakis et al., SURGICAL-MANAGEMENT FOR INSTABILITY AND PARAPLEGIA CAUSED BY SPINAL SARCOIDOSIS - A CASE-REPORT, Spine (Philadelphia, Pa. 1976), 23(15), 1998, pp. 1711-1714
Study Design. Report of a patient with paraplegia caused by vertebral
sarcoidosis. Objectives. To report a rare case of vertebral sarcoidosi
s accompanied by progressive neurologic symptoms from the lower extrem
ities, and to discuss the diagnostic and therapeutic approach to its m
anagement. Summary of Background Data. Vertebral sarcoidosis is a rare
condition, and only a few case reports exist in the literature, A nee
dle or open biopsy is required to establish the diagnosis. In most cas
es, treatment with steroids improves associated neurologic symptoms. O
perative intervention is necessary in cases with progressive vertebral
destruction, spinal instability, and impending or progressive neurolo
gic deterioration. Methods. Operative treatment by a two-stage anterio
r vertebrectomy and fusion followed by posterior stabilization was giv
en to a patient with vertebral sarcoidosis and progressive neurologic
deterioration of the lower extremities. Results, After surgery, the pa
tient had a complete neurologic recovery and satisfactory spinal fusio
n. Conclusions. In the absence of any spinal instability, neurologic s
ymptoms associated with vertebral sarcoidosis respond satisfactorily t
o nonoperative treatment with steroids. Progressive neurologic deterio
ration or spinal instability caused by bone destruction requires opera
tive intervention. Anterior vertebrectomy and fusion combined with pos
terior stabilization provided a satisfactory result for the patient in
this report.