We evaluated 3 patients with acromegaly who developed heart failure. H
eart failure appeared to be due to acromegalic cardiomyopathy in 2 pat
ients who did not have hypertension or evidence of coronary artery dis
ease, and it was possibly due to acromegalic cardiomyopathy combined w
ith familiar hypertrophic cardiomyopathy in 1 patient. The common echo
cardiographic findings in the present three cases were: 1) enlargement
of the left atrium, 2) markedly dilated left ventricular cavity with
diffuse hypokinesis, 3) decrease of indices of the left ventricular sy
stolic function, and 4) no evidence of left ventricular hypertrophy. E
chocardiographic findings in acromegaly with congestive heart failure
resemble those of idiopathic dilated cardiomyopathy,