ADVANCED PANCREATIC-CANCER SUCCESSFULLY TREATED WITH CONTINUOUS-INFUSION OF 5-FLUOROURACIL AND LOW-DOSE CISPLATIN

Citation
H. Kikuchi et al., ADVANCED PANCREATIC-CANCER SUCCESSFULLY TREATED WITH CONTINUOUS-INFUSION OF 5-FLUOROURACIL AND LOW-DOSE CISPLATIN, Internal medicine, 37(7), 1998, pp. 635-637
Citations number
7
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
09182918
Volume
37
Issue
7
Year of publication
1998
Pages
635 - 637
Database
ISI
SICI code
0918-2918(1998)37:7<635:APSTWC>2.0.ZU;2-M
Abstract
Due to pyloric stenosis in a 59-year-old male with the diagnosis of un resectable pancreatic head cancer, gastro-jejunostomy and cholecysto-j ejunostomy were performed. Following the operation, the patient underw ent a combination chemotherapy with cisplatin 10 mg/day x 5/week and c ontinuous infusion of 5-fluorouracil 500 mg/day for 4 weeks. After thr ee courses, the tumor size decreased and the serum carcinoembryonic an tigen (CEA) level decreased from 89.6 to 4.2 ng/ml without significant adverse effects. During the follow-up, the CEA increased and the pati ent is now receiving the same treatment, surviving for more than one y ear.