GENE CLUSTERS AND POLYCISTRONIC TRANSCRIPTION IN EUKARYOTES

Authors
BLUMENTHAL T
Citation
T. Blumenthal, GENE CLUSTERS AND POLYCISTRONIC TRANSCRIPTION IN EUKARYOTES, BioEssays, 20(6), 1998, pp. 480-487
Citations number
40
Categorie Soggetti
Biology,Biology
Journal title
BioEssays → ACNP
ISSN journal
02659247
Volume
20
Issue
6
Year of publication
1998
Pages
480 - 487
Database
ISI
SICI code
0265-9247(1998)20:6<480:GCAPTI>2.0.ZU;2-2
Abstract
Sometimes genes are arranged nonrandomly on the chromosomes of eukaryo tes. This review considers instances of gene clusters in which two gen es or more are expressed from a single promoter. This includes cases i n which a polycistronic pre-mRNA is processed to make monocistronic mR NAs in nematodes, as well as isolated examples of polycistronic mRNAs found in mammals, flies, and perhaps plants. (C) 1998 John Wiley & Son s, Inc.