TN5706, A TRANSPOSON-LIKE ELEMENT FROM PASTEURELLA-MULTOCIDA MEDIATING TETRACYCLINE RESISTANCE

Authors
KEHRENBERG C WERCKENTHIN C SCHWARZ S
Citation
C. Kehrenberg et al., TN5706, A TRANSPOSON-LIKE ELEMENT FROM PASTEURELLA-MULTOCIDA MEDIATING TETRACYCLINE RESISTANCE, Antimicrobial agents and chemotherapy, 42(8), 1998, pp. 2116-2118
Citations number
16
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
42
Issue
8
Year of publication
1998
Pages
2116 - 2118
Database
ISI
SICI code
0066-4804(1998)42:8<2116:TATEFP>2.0.ZU;2-F
Abstract
The 4,378-bp putative tetracycline resistance transposon Tn5706 of Pas teurella multocida consists of an internal tet(H)-tetR resistance gene region which is flanked by almost identical insertion elements, IS159 6 and IS1597. Two reading frames for proteins of 70 and 228 amino acid s were detected in each of these insertion sequence elements. The 228- amino-acid protein revealed homology to transposase proteins of gram-p ositive bacteria.