MOLECULAR CHARACTERIZATION OF A TEM-21 BETA-LACTAMASE IN A CLINICAL ISOLATE OF MORGANELLA-MORGANII

Authors
TESSIER F ARPIN C ALLERY A QUENTIN C
Citation
F. Tessier et al., MOLECULAR CHARACTERIZATION OF A TEM-21 BETA-LACTAMASE IN A CLINICAL ISOLATE OF MORGANELLA-MORGANII, Antimicrobial agents and chemotherapy, 42(8), 1998, pp. 2125-2127
Citations number
22
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
42
Issue
8
Year of publication
1998
Pages
2125 - 2127
Database
ISI
SICI code
0066-4804(1998)42:8<2125:MCOATB>2.0.ZU;2-M
Abstract
A clinical isolate of Morganella morganii, with reduced susceptibility to expanded-spectrum cephalosporins and aztreonam, was found to produ ce an extended-spectrum beta-lactamase with a pI of 6.4. The nucleotid e sequence of the encoding gene was that of the gene encoding TEM-21. This is the first molecular characterization of an extended-spectrum b eta-lactamase in M. morganii.