IN-VITRO ACTIVITIES OF THE KETOLIDE HMR-3647 AGAINST RECENT GRAM-POSITIVE CLINICAL ISOLATES AND HAEMOPHILUS-INFLUENZAE

Authors
BARRY AL FUCHS PC BROWN SD
Citation
Al. Barry et al., IN-VITRO ACTIVITIES OF THE KETOLIDE HMR-3647 AGAINST RECENT GRAM-POSITIVE CLINICAL ISOLATES AND HAEMOPHILUS-INFLUENZAE, Antimicrobial agents and chemotherapy, 42(8), 1998, pp. 2138-2140
Citations number
9
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
42
Issue
8
Year of publication
1998
Pages
2138 - 2140
Database
ISI
SICI code
0066-4804(1998)42:8<2138:IAOTKH>2.0.ZU;2-Y
Abstract
The ketolide HMR 3647 (previously RU 66647) was evaluated against 2,56 3 recent clinical isolates of gram-positive pathogens and 200 Haemophi lus influenzae isolates. HMR 3647 was active against macrolide-resista nt streptococci, including pneumococci, but was not active against mac rolide- or lincosamide-resistant staphylococci. Against H. influenzae, the potency of HMR 3647 was similar to that of azithromycin.