CONFIRMATORY EVIDENCE FROM 18S RIBOSOMAL-RNA GENE ANALYSIS FOR IN-VIVO DEVELOPMENT OF PROPAMIDINE RESISTANCE IN A TEMPORAL SERIES OF ACANTHAMOEBA OCULAR ISOLATES FROM A PATIENT

Authors
LEDEE DR SEAL DV BYERS TJ
Citation
Dr. Ledee et al., CONFIRMATORY EVIDENCE FROM 18S RIBOSOMAL-RNA GENE ANALYSIS FOR IN-VIVO DEVELOPMENT OF PROPAMIDINE RESISTANCE IN A TEMPORAL SERIES OF ACANTHAMOEBA OCULAR ISOLATES FROM A PATIENT, Antimicrobial agents and chemotherapy, 42(8), 1998, pp. 2144-2145
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
42
Issue
8
Year of publication
1998
Pages
2144 - 2145
Database
ISI
SICI code
0066-4804(1998)42:8<2144:CEF1RG>2.0.ZU;2-7
Abstract
DNA sequences of three 18S rRNA gene alleles present in trophozoites o btained before and after therapy for Acanthamoeba keratitis substantia te a previous report that the infection was due to a single Acanthamoe ba strain. Thus, the possibility that propamidine resistance which dev eloped during therapy was due to a mixed infection was ruled out.