INCORPORATION OF SERINOL DERIVED ACYCLIC NUCLEOSIDE ANALOGS INTO OLIGONUCLEOTIDES - INFLUENCE ON DUPLEX AND TRIPLEX FORMATION

Authors
BENHIDA R DEVYS M FOURREY JL LECUBIN F SUN JS
Citation
R. Benhida et al., INCORPORATION OF SERINOL DERIVED ACYCLIC NUCLEOSIDE ANALOGS INTO OLIGONUCLEOTIDES - INFLUENCE ON DUPLEX AND TRIPLEX FORMATION, Tetrahedron letters, 39(34), 1998, pp. 6167-6170
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
34
Year of publication
1998
Pages
6167 - 6170
Database
ISI
SICI code
0040-4039(1998)39:34<6167:IOSDAN>2.0.ZU;2-P
Abstract
Phosphoramidites 6a-c were readily prepared by an original route and u sed to incorporate serinol derived units I-III in oligonucleotides whi ch, compared to their natural analogues, exhibited a decreased hybridi zation capacity for duplex and tripler formation. (C) 1998 Elsevier Sc ience Lid. All rights reserved.