SCABRONINE-A, A NOVEL DITERPENOID HAVING POTENT INDUCTIVE ACTIVITY OFTHE NERVE GROWTH-FACTOR SYNTHESIS, ISOLATED FROM THE MUSHROOM, SARCODON-SCABROSUS

Authors
OHTA T KITA T KOBAYASHI N OBARA Y NAKAHATA N OHIZUMI Y TAKAYA Y OSHIMA Y
Citation
T. Ohta et al., SCABRONINE-A, A NOVEL DITERPENOID HAVING POTENT INDUCTIVE ACTIVITY OFTHE NERVE GROWTH-FACTOR SYNTHESIS, ISOLATED FROM THE MUSHROOM, SARCODON-SCABROSUS, Tetrahedron letters, 39(34), 1998, pp. 6229-6232
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
34
Year of publication
1998
Pages
6229 - 6232
Database
ISI
SICI code
0040-4039(1998)39:34<6229:SANDHP>2.0.ZU;2-L
Abstract
A novel diterpenoid, scabronine A, having strong inductive activity of the nerve growth factor synthesis was isolated from the fruit body of the mushroom, Sarcodon scabrosus (Fr.) Karat. The stereostructure of scabronine A (1) was elucidated on the basis of the spectroscopic anal ysis of natural scabronine A and its derivatives. (C) 1998 Elsevier Sc ience Ltd. All rights reserved.