A CHIRAL ANISOTROPIC REAGENT FOR DETERMINATION OF THE ABSOLUTE-CONFIGURATION OF A PRIMARY AMINO COMPOUND

Authors
HARADA K SHIMIZU Y FUJII K
Citation
K. Harada et al., A CHIRAL ANISOTROPIC REAGENT FOR DETERMINATION OF THE ABSOLUTE-CONFIGURATION OF A PRIMARY AMINO COMPOUND, Tetrahedron letters, 39(34), 1998, pp. 6245-6248
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
34
Year of publication
1998
Pages
6245 - 6248
Database
ISI
SICI code
0040-4039(1998)39:34<6245:ACARFD>2.0.ZU;2-3
Abstract
A chiral anisotropic reagent, -fluoro-2,4-dinitrophenyl-5-(R,S)-phenyl ethylamine ((R,S)-FDPEA, 2), was developed for determination of the ab solute configuration of the alpha-carbon of primary amino compounds. T his reagent has advantages over conventional reagents in terms of reac tivity, reliability and effectiveness, and was successfully applied to a peptide, microginin, produced by cyanobacteria. (C) 1998 Elsevier S cience Ltd. All rights reserved.