NEONATAL LUPUS SYNDROME - A CASE WITH CHONDRODYSPLASIA PUNCTATA AND OTHER UNUSUAL MANIFESTATIONS

Citation
E. Austinward et al., NEONATAL LUPUS SYNDROME - A CASE WITH CHONDRODYSPLASIA PUNCTATA AND OTHER UNUSUAL MANIFESTATIONS, Journal of Medical Genetics, 35(8), 1998, pp. 695-697
Citations number
15
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00222593
Volume
35
Issue
8
Year of publication
1998
Pages
695 - 697
Database
ISI
SICI code
0022-2593(1998)35:8<695:NLS-AC>2.0.ZU;2-Y
Abstract
We report a case of a newborn infant whose mother had systemic lupus e rythematosus (SLE) diagnosed before pregnancy. The child had clinical manifestations of neonatal lupus as well as chondrodysplasia punctata and other findings that resemble the congenital anomalies associated w ith the use of oral anticoagulants, with no history of exposure. We sp eculate that the combined action of the different maternal autoantibod ies may produce the whole spectrum of manifestations.