E. Austinward et al., NEONATAL LUPUS SYNDROME - A CASE WITH CHONDRODYSPLASIA PUNCTATA AND OTHER UNUSUAL MANIFESTATIONS, Journal of Medical Genetics, 35(8), 1998, pp. 695-697
We report a case of a newborn infant whose mother had systemic lupus e
rythematosus (SLE) diagnosed before pregnancy. The child had clinical
manifestations of neonatal lupus as well as chondrodysplasia punctata
and other findings that resemble the congenital anomalies associated w
ith the use of oral anticoagulants, with no history of exposure. We sp
eculate that the combined action of the different maternal autoantibod
ies may produce the whole spectrum of manifestations.