FUNCTIONS OF AT(2) RECEPTORS OF ANGIOTENSIN-II

The structure, the coding gene and expression of the AT(2) subtype rec eptor of angiotensin II have been described recently; however, the pos sible role of this receptor remains unclear despite its presence in mo st mammalian tissues. The AT(2) receptor is probably involved in fetal growth and adult tissue repair and remodelling, especially in the car diovascular system. There are still conflicting results, in vitro and in vivo, as to whether AT(2) receptors limit and/or accelerate the gro wing processes in the cardiovascular tissues.