ANIMAL-MODELS OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS

Authors
GRUNIG G CORRY DB COFFMAN RL RENNICK DM KURUP VP
Citation
G. Grunig et al., ANIMAL-MODELS OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS, Immunology and allergy clinics of North America, 18(3), 1998, pp. 661
Citations number
104
Categorie Soggetti
Allergy,Immunology
Journal title
Immunology and allergy clinics of North America → ACNP
ISSN journal
08898561
Volume
18
Issue
3
Year of publication
1998
Database
ISI
SICI code
0889-8561(1998)18:3<661:AOABA>2.0.ZU;2-E
Abstract
Animal models of ABPA provide an intriguing insight into disease patho genesis across various species. In the mouse, the availability of gene -targeted animals allows for a detailed dissection of critical cells a nd cytokines that mediate immunopathology. T cells are the central eff ecters that ultimately induce lung pathology and airway hyperreactivit y in murine ABPA.