COMBINATORIAL PROTEIN DESIGN BY IN-VITRO RECOMBINATION

Authors
GIVER L ARNOLD FH
Citation
L. Giver et Fh. Arnold, COMBINATORIAL PROTEIN DESIGN BY IN-VITRO RECOMBINATION, Current opinion in chemical biology, 2(3), 1998, pp. 335-338
Citations number
26
Categorie Soggetti
Biology,Biophysics
Journal title
Current opinion in chemical biology → ACNP
ISSN journal
13675931
Volume
2
Issue
3
Year of publication
1998
Pages
335 - 338
Database
ISI
SICI code
1367-5931(1998)2:3<335:CPDBIR>2.0.ZU;2-U
Abstract
DNA recombination is a powerful engine for the creation of new phenoty pes. Recently, methods for in vitro DNA recombination (DNA shuffling) have been developed and applied to the evolution of novel molecules in the laboratory. An exciting new development is the shuffling of homol ogous genes to create diversity for directed evolution.