ANALYZING GENETIC INFORMATION WITH DNA ARRAYS

Citation
Sc. Casegreen et al., ANALYZING GENETIC INFORMATION WITH DNA ARRAYS, Current opinion in chemical biology, 2(3), 1998, pp. 404-410
Citations number
39
Categorie Soggetti
Biology,Biophysics
ISSN journal
13675931
Volume
2
Issue
3
Year of publication
1998
Pages
404 - 410
Database
ISI
SICI code
1367-5931(1998)2:3<404:AGIWDA>2.0.ZU;2-J
Abstract
The large amount of DNA sequence information produced in recent years has created a need for high-throughput methods in biology and genetics . These include sequencing, comparing gene sequences and genotyping. D NA arrays promise a highly parallel means for analysis of DNA that is fast and cost-effective, and offers scope for application to complex s ystems and processes. Recent years have seen continued transfer of tec hnology from the microelectronics industry. Rapid application of the t echnology to genotyping, antisense oligonucleotide selection and gene expression analysis has illustrated the general power of this approach .