The large amount of DNA sequence information produced in recent years
has created a need for high-throughput methods in biology and genetics
. These include sequencing, comparing gene sequences and genotyping. D
NA arrays promise a highly parallel means for analysis of DNA that is
fast and cost-effective, and offers scope for application to complex s
ystems and processes. Recent years have seen continued transfer of tec
hnology from the microelectronics industry. Rapid application of the t
echnology to genotyping, antisense oligonucleotide selection and gene
expression analysis has illustrated the general power of this approach
.