CELL-ADHESION MOLECULES IN CORD-BLOOD HEMATOPOIETIC PROGENITORS

Authors
TIMEUS F CRESCENZIO N MARRANCA D DALLAGLIO M FAZIO L DIMARCO M SARACCO P RICOTTI M GABUTTI V
Citation
F. Timeus et al., CELL-ADHESION MOLECULES IN CORD-BLOOD HEMATOPOIETIC PROGENITORS, Bone marrow transplantation, 22, 1998, pp. 61-62
Citations number
6
Categorie Soggetti
Hematology,Oncology,Immunology,Transplantation
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
22
Year of publication
1998
Supplement
1
Pages
61 - 62
Database
ISI
SICI code
0268-3369(1998)22:<61:CMICHP>2.0.ZU;2-9
Abstract
We investigated the expression of different cell adhesion molecules on cord blood (CB) and bone marrow (BM) CD34(+)/CD38(+) and CD34(+)/CD38 (-) cells. CD11a and CD62L mere more expressed in CB than in BM CD34()/CD38(-) subset, suggesting a possible advantage in homing and engraf tment, A short exposure to various cytokines increased CD62L expressio n only in the more differentiated CB and BM CD34(+)/CD38(+) cells.