UMBILICAL-CORD BLOOD (UCB) TRANSPLANT FROM UNRELATED MISMATCHED DONORIN PATIENTS WITH HIGH-RISK (HR) LEUKEMIA

Authors
IORI AP SCRENCI M GUGLIELMI C MENGARELLI A CARMINI D TESTI AM MOLETI ML CIMINO G PERRONE P LAURENTI L ELIA L BOECKLIN F ROMANO A VULCANO F DEFELICE L ARCESE W
Citation
Ap. Iori et al., UMBILICAL-CORD BLOOD (UCB) TRANSPLANT FROM UNRELATED MISMATCHED DONORIN PATIENTS WITH HIGH-RISK (HR) LEUKEMIA, Bone marrow transplantation, 22, 1998, pp. 75-75
Citations number
NO
Categorie Soggetti
Hematology,Oncology,Immunology,Transplantation
Journal title
Bone marrow transplantation → ACNP
ISSN journal
02683369
Volume
22
Year of publication
1998
Supplement
1
Pages
75 - 75
Database
ISI
SICI code
0268-3369(1998)22:<75:UB(TFU>2.0.ZU;2-9
Abstract
Ten consecutive children with high risk leukemia have been submitted t o UCB transplant from unrelated HLA mismatched donors. All patients re ceived an identical regimen for conditioning and GVHD prophylaxis, The median dose of viable nucleated cells infused was 2.6 x 10(6)/kg b.w. Among the nine patients evaluable for engraftment the hematopoiesis w as of full donor origin in six patients and autogolous in three. At a median follow-up of 9 months, six of nine (67%) patients are alive in CR.