L. Lesueur et al., PREDICTABILITY OF AMBLYOPIA IN AMETROPIC CHILDREN - A REVIEW OF 96 CASES, Journal francais d'ophtalmologie, 21(6), 1998, pp. 415-424
Purpose The aim of this cross-sectional retrospective study was to ana
lyze the predictability of amblyopia in children with myopic and hyper
opic unilateral and bilateral ametropia. Materials and methods One hun
dred and sixty two eyes of 96 children, (mean age: 8.6 years), were in
cluded in this work Mean visual acuities and significant refractive er
rors were estimated for all the cases. The frequency of amblyopia and
strabismus was studied in cases without amblyopia and in cases with me
dium and high grade amblyopia. Results Mean visual acuities were signi
ficantly higher in cases of bilateral myopia (p < 0.001) and hyperopia
(p < 0.05) compared with unilateral ametropia. The frequency of myopi
c eyes (p < 0.01) eyes with high grade of myopia (p < 0.002) and aniso
myopic eyes (p < 0.001) was significantly higher in cases of high ambl
yopia compared with cases without amblyopia. Strabismus (p < 0.05) wer
e also significantly more frequent in cases of high amblyopia as well
as in cases of myopic eyes (p ( 0.01). Moreover, in the group of high
amblyopia, 6 cases (6/7) had developed an intolerance for contact lens
es. Conclusions The risk of developing high grade amblyopia appeared s
ignificantly associated with unilateral medium and high level myopia.
Strabismus and difficulties with good correction of anisometropia by c
ontact lenses or spectacle appeared to be predisposing factors. This o
bservation would suggest the indication of refractive surgery might be
useful in these particular cases. To conclude, this study emphasizes
the importance of early treatment of ametropia to reduce the incidence
of amblyopia in children.