Sb. Magill et al., COCCIDIOIDOMYCOSIS-INDUCED THYROIDITIS AND CALCITRIOL-MEDIATED HYPERCALCEMIA IN A HEART-TRANSPLANTATION PATIENT, The Endocrinologist, 8(4), 1998, pp. 299-302
A 56-year-old man with a history of cardiac transplantation developed
disseminated coccidioidomycosis involving the upper extremities, Suppr
ession of thyrotropin was followed by marked biochemical hypothyroidis
m. Biopsy of an enlarged left thyroid lobe demonstrated infiltration w
ith coccidioidomycosis, He also developed hypercalcemia thought to be
mediated by 1,25-dihydroxyvitamin D and was treated with a bisphosphon
ate. This rare case of disordered calcium metabolism and thyroiditis s
hould alert physicians of the potential endocrinopathies that can deve
lop in patients who have undergone solid organ transplantation.