BIOTRANSFORMATIONS WITH RHIZOPUS-ARRHIZUS - PREPARATION OF THE ENANTIOMERS OF 1-PHENYLETHANOL AND 1-(O-METHOXYPHENYL, M-METHOXYPHENYL AND P-METHOXYPHENYL) ETHANOLS

Authors
SALVI NA PATIL PN UDUPA SR BANERJI A
Citation
Na. Salvi et al., BIOTRANSFORMATIONS WITH RHIZOPUS-ARRHIZUS - PREPARATION OF THE ENANTIOMERS OF 1-PHENYLETHANOL AND 1-(O-METHOXYPHENYL, M-METHOXYPHENYL AND P-METHOXYPHENYL) ETHANOLS, Tetrahedron : asymmetry, 6(9), 1995, pp. 2287-2290
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
9
Year of publication
1995
Pages
2287 - 2290
Database
ISI
SICI code
0957-4166(1995)6:9<2287:BWR-PO>2.0.ZU;2-E
Abstract
The fungus Rhizopus arrhizus has been used for the reduction of acetop henone anti its o-, m- and p-methoxy derivatives 1a-d to the correspon ding (S)-(-)-alcohols. Their racemic acetates were also hydrolyzed to (R)-(+)-alcohols. The analysis of products revealed that maximum enant ioselectivity (78-88% ee) could be obtained using m-methoxy acetopheno ne as substrate.